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These companies are expected to join us for investor day at TMC Innovation on May 14, 2026. This list is subject to change. Please email Alianys Rosario (arosario@tmc.edu) with any questions. Companies in bold are TMC Venture Fund Portfolio companies.


Medical Device

Pre-Seed

    • OrganGuard, Houston, TX // preventing hospital-acquired acute kidney injury and saving the healthcare system billions in avoidable cost.
    • Peripear ltd , Oxford, UK / / preventing birth injury affecting 2.5M US women annually, $2.6B market, with automated thermal wearable device.
    • Fluens Medical Inc., Houston, TX / / developing a fully implantable, energy-autonomous device that continuously manages ascites a deadly liver complication, eliminating the need for repeated drainage procedures and improving quality of life for liver disease patients as a bridge to a liver transplant.
    • Freyya, Inc. , Salt Lake City, Utah and San Antonio, TX / /  commercializing a tampon-like wearable, real-time monitoring device designed to rehabilitate the pelvic floor.
    • Additive Biomedical Corporation, Houston, TX / / OptiLung is making the world's safest artificial lung.
    • Xander Medical, Williston, VT / /  redefining spinal surgery with proprietary surgical screws engineered for reliable removal following critical implant failures.
    • GuardianOrtho, Houston, TX / / The first and only under-cast platform delivering precision thermal therapy and real-time complication monitoring ‚ where no alternative exists.

Seed

    • Noleus Technologies, Houston, TX / / clinical stage company developing novel therapies to treat unmet clinical needs utilizing a platform of internal negative pressure therapy with the first unmet need being post operative ileus.
    • AcuSurgeon, Houston, TX / / easy-to-use, consistently fastest iSpeed laparoscopic-robotic port closure system with iSpeed sutures.
    • OrganVive, Houston, TX / /  next-generation organ preservation technology and a new delivery/assessment paradigm that increases usable organs and improves transplant decisions.
    • SageSpectra, Houston, TX / /  transforming tissue perfusion into a continuous vital sign that allows clinicians to detect deterioration earlier and deliver safer, more effective care.
    • Rhythio Medical Technologies, Inc, Houston TX / / the Rhythio Injectable Electrode, a Breakthrough Designated Device by the FDA, is on track to revolutionize cardiac care in heart failure patients.
    • Roam Technologies, Sydney, NSW, Australia / /  pioneering a new way to deliver oxygen;next-generation tankless oxygen device for active, everyday use in chronic conditions- our mission is to enable millions to breathe better and live longer, fuller lives.
    • Convergent Medical Inc., Houston, TX / /  KCI-caliber technology meets the $4.1B Ostomy market with first disruptive innovation in 30 years.
    • ACT Medical, Cambridge, UK / /  a patented haemorrhage-control technology addressing a $4.7B U.S. civilian and military penetrating-wound market.
    • Bairitone Health, Houston, TX  / /  we remove the guesswork from sleep apnea care by bringing anatomy imaging to the home environment.
    • Cardiost, Inc., Houston, TX / /  building a fully implantable, pressure-based circulatory support platform for heart-failure patients underserved by current therapies.
    • Corveus Medical, Houston, TX / /  developing a minimally invasive device that addresses a root cause of heart failure, enabling improved patient outcomes, fewer hospitalizations, and halted disease progression.(Seed → Preparing for Series A Q2 2026).
    • Lifelet Medical, Galway, Ireland / / on a mission to enable one valve for life for patients with heart valve disease through excellence in polymer science and engineering. (Seed → Raising Series A)
    • Aspira Medical, Houston, TX / / Preventing aspiration pneumonia in the ICU through wearable ultrasound monitoring. 
    • ScubaTx, Houston, TX and Manchester, England / /  built the next-generation organ preservation technology and a new delivery/assessment paradigm that increases usable organs and improves transplant decisions.
    • Surf Therapeutics, Austin, TX / / ultrasound neuromodulation platform to restore immune balance. 

Series A

    • Motif Neurotech, Houston, TX / /  building the world's first therapeutic brain-computer interface (BCI) to treat drug-resistant mental health conditions. Motif is on track to start US clinical trials with a proprietary chronic implant less than 4 years after founding making Motif the fastest and most capital efficient modern neurotech company to reach this milestone.
    • CorInnova, Inc., Houston, TX  / /  minimally invasive, non-blood contacting cardiac assist device unlocks a $5B acute heart failure market by treating patients existing devices cannot treat today.
    • Endomedix, Inc., Montclair, NJ / /  developed a device that eliminates 3 of the weaknesses of current devices that lead to costly complications and reduces the impact of a 4th source of complications.
    • Spatium Medical, Rotterdam, The Netherlands / /  Dutch Erasmus MC spin-off, introducing the new standard of care in medical insufflation, this year in the US first.
    • PATH EX, Inc., Houston, TX / /  developing a breakthrough blood purification device that rapidly removes bacteria from the bloodstream to improve outcomes in patients with sepsis.

    Series B+

    • Prana Surgical, Houston, TX / /  an image-guided, minimally invasive surgical platform designed to precisely remove early lung nodules while preserving healthy tissue and enabling more personalized treatment. 
    • Wellysis USA Inc., Houston, TX / /  samsung SDS spinoff company that uses Samsung HealthProcessor. We created the smallest, lightest device that can be patched on the chest and uses AI to help physicians to quickly identify irregular rhythms.

    Additional companies are expected to participate Investor Day - final list to be provided by Alianys Rosario (arosario@tmc.edu) or Emily Reiser (ereiser@tmc.edu)

     

Digital Therapeutics / Diagnostic 

Pre-Seed

    • NeuroAcoustics, Houston, TX / / harnessing AI-powered neuromodulation to restore brain health during sleep

 

Other TMC Innovation Companies

The following will not be participating in the Spring Investor Day but are available for introduction:

          Seed

    • Vivifi Medical, Inc, Houston, TX / / first non-urethral, office-based, root-cause treatment for Benign Prostatic Hyperplasia (BPH).